Intensive luteal phase support after GnRH agonist trigger: it does help

I-27: GnRH Agonist Triggering and Luteal Phase Support

Background GnRH agonist triggering is one of the strategies for ovulation triggering and final maturation of oocytes. So , should be notice for luteal phase support in these cycles. At the first it was began for prevention of severe OHSS but it was associated with luteal phase problem and lower pregnancy rate due to luteolysis effects of GnRH agonists. So, two other alternative strategies have ...

'Luteal coasting' after GnRH agonist trigger - individualized, HCG-based, progesterone-free luteal support in 'high responders': a case series.

This study reports 21 IVF cases with excessive ovarian response, who received gonadotrophin-releasing hormone agonist (GnRHa) triggering for final oocyte maturation, followed by a human chorionic gonadotrophin (HCG)-based, progesterone-free, luteal support, individually timed ('luteal coasting') according to endogenous luteal progesterone concentrations. One patient developed a brief early-onse...

Luteal phase support after GnRH triggering in IVF cycles

Corespondență: Dr. Andreea Carp Velișcu e-mail: andreea_veliscu@ yahoo.com Introduction. The luteal phase in IVF stimulated cycles is very different from that in natural cycles, so is very important to mimic the perfect condition for pregnancy. Method. Since January 2015 until December 2015, we have 88 cycles in which the triggering was done with GnRH agonist. We performed an embriotransfer in ...

The Luteal Phase after GnRHa Trigger-Understanding An Enigma

GnRH agonist ovulation trigger and hCG-based, progesterone-free luteal support: a proof of concept study.

BACKGROUND It is now well established that a GnRH agonist (GnRHa) ovulation trigger completely prevents ovarian hyperstimulation syndrome. However, early studies, using conventional luteal support, showed inferior clinical results following a GnRHa trigger compared with a conventional hCG trigger in normal responder IVF patients. We here present a novel approach for luteal support after a GnRHa...